Cellular responses toBrugia infections inMeriones unguiculatus

Cellular immune responses during gonococcal and meningococcal infections.

The genus Neisseria contains two species of clinical importance: Neisseria gonorrhoeae and Neisseria meningitidis. Although these two microorganisms are closely related genetically, the diseases they produce differ greatly. N. gonorrhoeae is the etiologic agent of gonorrhea, currently among the most common of the classical sexually transmitted diseases, whereas N. meningitidis is the causative ...

Effects of Surface Viscoelasticity on Cellular Responses of Endothelial Cells

Background: One area of nanoscience deals with nanoscopic interactions between nanostructured materials and biological systems. To elucidate the effects of the substrate surface morphology and viscoelasticity on cell proliferation, fractal analysis was performed on endothelial cells cultured on nanocomposite samples based on silicone rubber (SR) and various concentrations of organomodified nano...

Initiating Cellular Stress Responses

The phosphoinositide 3-kinase related kinases (PIKKs) mediate responses to diverse stresses, including DNA double-strand breaks (DSBs), abnormal replication fork progression, the recognition of premature termination codons in mRNAs, and inadequate nutrient availability. Rigorous control of these kinases limits cellular damage and promotes cell viability in the presence of stress. Control mechan...

Cellular Stress Responses

Kinetics of cellular responses to intraperitoneal Brugia pahangi infections in normal and immunodeficient mice.

Filarial infections evoke exuberant inflammatory responses in the peritoneal cavities of immunocompetent mice. Clearance of infection appears to be dependent on complex interactions between B1 and B2 B lymphocytes, T cells, eosinophils, macrophages, and the products of these cells. In an earlier communication, we described the course of infection in normal immunocompetent mice. In this study, w...